Magnesium Oxide
A to Z Drug Facts
Magnesium Oxide |
(mag-NEE-zee-uhm OX-ide) |
Mag-Ox 400, Maox, Uro-Mag |
Class: Antacid |
Action Neutralizes gastric acid, thereby increases pH of stomach and duodenal bulb; also increases lower esophageal sphincter tone.
Indications Symptomatic relief of upset stomach associated with hyperacidity, including heartburn, gastroesophageal reflux, acid indigestion and sour stomach; relief of hyperacidity associated with peptic ulcer, gastritis, peptic esophagitis, gastric hyperacidity and hiatal hernia. Also used for treatment of hypomagnesemia, or magnesium depletion resulting from malnutrition, restricted diet, alcoholism or magnesium-depleting drugs.
Contraindications Standard considerations.
ADULTS: PO 140 mg (caps) 34 times/day or 400840 mg/day (tabs).
Iron: Decreased pharmacological effect of iron. Nitrofurantoin: Decreased pharmacological effect of nitrofurantoin. Penicillamine: Decreased pharmacological effect of penicillamine. Tetracyclines: Decreased pharmacological effect of tetracyclines.
Lab Test Interferences None well documented.
GI: Laxative effect (diarrhea); rebound hyperacidity. META: Hypermagnesemia. OTHER: Milk-alkali syndrome.
Pregnancy: Category B. Lactation: Undetermined. Renal insufficiency: Caution with renal impairment to avoid hypermagnesemia and toxicity.
PATIENT CARE CONSIDERATIONS |
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Copyright © 2003 Facts and Comparisons
David S. Tatro
A to Z Drug Facts